Are Antiplatelet Agents Beneficial in Prevention of Infective Endocarditis?
نویسندگان
چکیده
منابع مشابه
Prophylaxis of experimental endocarditis with antiplatelet and antithrombin agents: a role for long-term prevention of infective endocarditis in humans?
BACKGROUND Infective endocarditis (IE) mostly occurs after spontaneous low-grade bacteremia. Thus, IE cannot be prevented by circumstantial antibiotic prophylaxis. Platelet activation following bacterial-fibrinogen interaction or thrombin-mediated fibrinogen-fibrin polymerization is a critical step in vegetation formation. We tested the efficacy of antiplatelet and antithrombin to prevent exper...
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The undiminished incidence of streptococcal endo-carditis in this country is a testimony to the failure of prophylaxis. Ninety per cent or more of medical infective endocarditis in the UK is still caused by the viridans group of streptococcil though in the United States the incidence has fallen to 50 per cent in some series probably because of a rise in the relative incidence of cases caused by...
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Infective endocarditis is an uncommon heart disease with a variable incidence, mostly related to the ever-increasing development of cardiac surgery and the longer survival of patients with congenital heart disease (CHD). Thirty-seven episodes of infective endocarditis (IE) were evaluated in 36 children (under 15 years of age) admitted to hospitals affiliated to Shiraz University of Medical ...
متن کاملINFECTIVE ENDOCARDITIS IN CHILDREN
A total of 14 cases of infective endocarditis (IE) in children aged 6 months to 10 years were seen from December 1987 to December 1992 at the pediatric unit of Ayatollah Taleghani Medical Center. The majority of patients (12 of 14) were between 5 and 10 years of age. Acyanotic congenital heart disease was known to preexist in 78.6% and rheumatic valvular heart disease in 21.4% of cases. Or...
متن کاملPrevention of infective endocarditis in developing countries
Infective endocarditis (IE) causes substantial morbidity and mortality despite modern antimicrobial chemotherapy and advances in the ability to diagnose and treat complications. Prevention of IE is, therefore, very important. Infective endo-carditis usually develops following a bacteraemia in individuals with underlying structural cardiac defects. Bacteraemia may occur spontaneously, follow eve...
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ژورنال
عنوان ژورنال: JAMA Cardiology
سال: 2019
ISSN: 2380-6583
DOI: 10.1001/jamacardio.2019.3130